Multi-Stakeholder Partnerships (MSPs) have been touted by the UN as a sure way for harnessing synergy to realise the 17 Global Goals. Goal 17 aims to achieve Global Partnership. Targets 17.16 to 17.17 are specifically dedicated to MSPs. They identify, public, private and civil society partnership as a means to boost critical factors, which would equip states to achieve the goals. These include, financial resource mobilisation, technology and sharing of knowledge and expertise. Given the importance of state ownership in Agenda 2030, states are mandated to facilitate these partnerships, thus acting as conveners to provide a reliable avenue for multi-stakeholder engagements. Using a qualitative methodology to acquire primary and secondary data, this study, therefore, focused on how the Government of Ghana (GoG) is enabling MSPs within its borders. The study found that, the GoG is pursuing MSPs in a decentralised and inclusive framework. While strides have been made, there are some challenges that have to be addressed.