CHAPTER ONE
1.0 INTRODUCTION
1.1 BACKGROUND OF STUDY
Soybean is one of the most economical and nutritious foods which can combat the diseases stemming from malnutrition and the nutraceutical ingredients present in it and can reduce the risk of major chronic diseases like cancer, atherosclerosis, osteoporosis and diabetes (Vineet, 2007). Soybean is an excellent source of quality protein and compares well with animal protein in essential amino acids pattern with the exception of sulphur containing amino acids. Soybean is the concentrated source of vegetable proteins. It contains about 40%protein and 20% oil.
Proteins are abundantly rich in lysine which is a limiting amino acid in most of the cereals. Soy fat being highly unsaturated has been found to be nutritionally desirable. Therefore, it can easily supplement the diet of poor Indians (Chauhan, 2005). It has high proportion of unsaturated fatty acids, such as linoleic and linolenic acids, it is considered as highly healthful oil. The ratio of polyunsaturated fatty acid to saturated fatty acid is 82:18, which is highly conducive to lower the blood cholesterol. Soy food contains most of the desirable characteristics therefore; it may be treated as consummate functional food.
Soybean also contains many minor substances, which are biologically active non nutritive components known as “phytochemicals”, “isoflavones” or “phytoestrogen” also known as coumesterol or “plant estrogen” very similar to that of female sex hormone estrogen) with very weak activity of estrogen, which offers unique health benefits.
Soybean is a good source of niacin, riboflavin, iron, potassium, calcium, magnesium, and phosphorous with several fat and water soluble vitamin Bcomplex (Tripathi, 2005). Soybeans are often called the “miracle crop.” They are the world’s foremost provider of vegetable protein and oil. The bushy, green soybean plant is a legume related to peas, groundnuts (peanuts) and alfalfa.
Soybeans are included in the category of oilseed, which is a generic reference to crops with seeds that can produce edible and/or non-edible oil in economic quantities. The most versatile of the world’s major crops, soybeans can be grown in a wider variety of soil and climatic conditions than any other major world crop. Consequently, soybeans are the most widely grown oilseed in the world. In the last 20 years, scientists have learned how to extract a much wider variety of byproducts from soybeans that are proving beneficial in animal feed, human food and industrial applications.
Rats have a long history in medical research. They were the first mammalian species specifically domesticated to be used in the laboratory. They are thought to have originated in some parts of Asia; Rattusrattus was well established in Europe by 1100 A.D., with Rattus norvegicus commonly found in Europe in the 1700s. By the 1800s, these animals were used for neuro-anatomy studies in the United States and in Europe. It was in the late 1800s and early 1900s that individual stocks and strains had their beginnings (Animals in research, 2013; Sengupta, 2013).
The success of the rat in research today has been linked to the Wistar Institute in the United States of America, when in 1906, the institute developed the Wistar albino strain (Rattus norvegicus) (The Wistar Institute: History, 2007). Currently, there are 117 albino strains of the laboratory rat, all of which can be traced genetically back to the one rat, likely to have arisen as a mutation from a hooded (piebald) rat strain (Animals in research, 2013).
1.2 STATEMENT OF THE PROBLEM
Soy bean is a legume that is very rich in vitamins and when mixed with other grains to be used as a complementary food can also improve hormonal functionality. But in a situation of determining the effect of it in hormonal growth of rat becomes a little bit problematic in the sense that there might be inadequate instrument for the experiment to be carried out, secondly might be that there might be no competent hands in the laboratory to carry out the experiment. Thirdly could be that there are no good laboratory set up to carry out all the necessary experiment needed. Finally, there have been several research carried out on the effect of soya bean but there have been no single research carried out on the effect of soy groundnut mixed grain complementary food on the level of selected food on the growth of hormones in male weaning wistars rat.
EFFECT OF SOY GROUNDNUT MIXED GRAIN COMPLEMENTARY FOOD ON THE LEVEL OF SELECTED GROWTH IN MALE WEANING WISTAR RATS
