The role that vitamin D plays in numerous biological systems has been an intriguing topic in recent decades. Currently, scientists are researching its interaction with the central nervous system, and in particular, the ageing brain. Substantial data from animal research exist on the physiologic effects of vitamin D on the neurological system. It is postulated that this vitamin may influence cognitive function in humans. Methods: Using the search terms “vitamin D” and “cognitive function,” an exhaustive literature search was performed using the following databases: Medline-OVID, Web of Science, MD Consult, CINHAL, and PsycINFO. Any other scientific terms that can be used for these two terms were searched, as well, including but not limited to “cholecalciferol” and “cognition” and “cognitive decline” so that relevant research articles were not overlooked.
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