THE ROLE OF VITAMIN C IN FATTY ACID OXIDATION

TABLE OF CONTENTS

Title Page    –        –        –        –        –        –        –        –        –        i

Certification         –        –        –        –        –        –        –        –        –        ii

Dedication –        –        –        –        –        –        –        –        –        iii

Acknowledgements        –        –        –        –        –        –        –        iv-v

Table of Contents –        –        –        –        –        –        –        –        vi-viii

CHAPTER ONE: INTRODUCTION

CHAPTER TWO

• STRUCTURE AND FUNCTION OF VITAMIN C                6-8
  • Biochemical Roles of Vitamin C       –        –        –        –        8-11
    • Vitamin C as an Antioxidant  –        –        –        –        –        11-13
    • Collagen Synthesis        –        –        –        –        –        –        13-15
    • Absorption of Iron        –        –        –        –        –        –        15-17
  • Sources of Vitamin C    –        –        –        –        –        –        17-18
  • Dietary Recommendation for Vitamin C    –        –        –        19-22
  • Deficiency of Vitamin C –        –        –        –        –        –        22-23

CHAPTER THREE

• THE ROLE OF VITAMIN C IN FATTY ACID OXIDATION       24-29
  • Fatty Acid Oxidation     –        –        –        –        –        –        29-30

3.2     Transportation of Fatty Acid from the Cytosol to

the Mitochondria           –        –        –        –        –        –        30-32

• Vitamin C and Fatty Acid Oxidation                   –        –        –        32-35
  • The Role of Carnitine    –        –        –        –        –        –        35-37
  • Vitamin C Deficiency and Fatty Acid Oxidation  –        –        37-39

CHAPTER FOUR: SUMMARY AND CONCLUSION

• Summary             –        –        –        –        –        –        –        40
  • Conclusion           –        –        –        –        –        –        –        40-41
  • Recommendations                   –        –        –        –        –        –        41

References

CHAPTER ONE

INTRODUCTION

1.0     Background of the Study

The prevalence of overweight and obesity has risen at an alarming rate over the past couple of decades in the United States (Wang et al., 2008). Consequently, the incident of weight – related health complications such as heart disease, diabetes and cancer has risen as well (Wang et al., 2008: Garcia et al. 2009), leading to a dramatic increase in health care costs. In facts, the average annual health care cost of an obese individual in the United States is over $1000 higher than that of a normal weight individual (Wang et al. 2008). Considering the urgency in of this problem, it is clear that further research is essential in order to better understand the physiological mechanisms responsible for weight loss and healthy weight maintenance.

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