ABSTRACT
The recurrent nature of yeast infections and the subsequent use of antifungal medicines for treatment, pose a potential threat to women’s health and safety worldwide, which could also give rise to antifungal resistance. The aim of this study is to evaluate the antimicrobial efficacy of garlic and tumeric against multi-drug resistance of Candida albicans, associated with Vulvovaginal infection. Results iof the anti-microbial susceptibility test by disc diffusion method revealed that ethanolic extract of both herbal products, was generally more effective in inhibiting the growth iof Candida albicans. As observed from the results, garlic was 1.3 times, more effective than turmeric, at a concentration of 400mg/ml. In iaddition, each of the concentrations of ethanolic extract of garlic was more effective thanithe corresponding concentrations of tumeric extract. The antimicrobial activity of the garlic extract displayed more effective result against Candida albicans. The minimum inhibitory concentration test was carried out using concentrations of 200mg/ml of each extract and the MIC was observed at concentration of 6.1 and 7.1 of the garlic for both ethanol and aqueous extract and for the tumeric it was observed at concentration of 4.1 and 5.1 for both ethanolic and aqueous extract. In addition, natural products such as garlic and tumeric promise a great alternation in the future as a compliment to antifungal drug in the treatment of vulvovaginal candidiasis. The reason is because garlic contains allicin, which is one of the active principles that homogenate a variety of antimicrobial activities. Allicin inhibits the growth of fungal and bacterial activities.
COMPARATIVE ASSESSMENT OF THE INHIBITORY POTENTIALS OF GARLIC AND TUMERIC IN TREATMENT OF VULVOVAGINAL CANDIDIASIS
